Have you ever been stunned as it seemed you were killed by one Battle Rifle shot or just a few plugs from an SMG? You were probably already hit by the Plasma Pistol.
Killer Plasma An excellent way to accumulate some quick kills on Xbox Live Multiplayer is to use the Plasma Pistol (the small Covenant gun that shoots green plasma) in combination with another weapon. Dual-wield the gun with an SMG. Fully charge the Plasma Pistol and use it's homing properties to easily hit someone. Then it will only take a second with the SMG to finish the job as the enemy's Energy Shield will be almost gone. I've found this tactic works great in a map such as Beaver Creek or in close range combat.
Alternately, in larger maps such as Colossus, shoot with a Plasma Pistol and carry a Battle Rifle as your backup weapon. Quickly switch over to your Battle Rifle after you shoot your Plasma Pistol and one shot will finish things. This variation allows you to zoom in with your scope for long range accuracy.
Bonus Tip! This technique also works just as well on someone who has the Overshield!